Vitamin B12 Synergy lozenges combine 3 forms of vitamin B12: methylcobalamin, adenosylcobalamin and hydroxocobalamin.

The sublingual absorption via the oral mucosa and the broad-spectrum efficacy of these three forms of vitamin B12, ensure optimal vitamin B12 supply.

Vitamin B12 Synergy is ideal for those who suffer from digestive disorders in the gastrointestinal tract, yet strive to achieve the most effective vitamin B12 supply possible.

• contains the 3 natural forms of vitamin B12
• provides a total of 1200 µg of vitamin B12 per lozenge
• sublingual absorption is ideal for those with gastrointestinal problems
• gentle on the teeth, as it is sweetened with xylitol
• free of any flavors
• suitable for vegetarians, vegans and diabetics

Vitamin B12 Synergy contains the two bioactive forms of vitamin B12: methylcobalamin and adenosylcobalamin, which are active in the body, without having to be converted.

In addition, it delivers hydroxocobalamin, which binds itself to transport molecules in the body, and thereby becomes a depot-storage form of B12. If required, it can be converted into the two active forms of B12, methylcobalamin or adenosylcobalamin.

This naturally active co-enzyme form of vitamin B12 is active, especially in the cytoplasm, in the brain and in the nervous system. There it is responsible for the protection and regeneration of the nerves, the formation of neurotransmitters and the production of the genetic materials DNA and RNA.

Methylcobalamin is also responsible for the reactivation of folic acid, which is why a B12 deficiency can lead to folic acid deficiency. Methylcobalamin is also needed to convert homocysteine to methionine.

Methionine is a precursor of S-adenosylmethionine (also called SAM or SAMe), which releases its methyl group to a variety of enzymes. These, in turn, are involved in detoxification, regulation of the enzymes and the biosynthesis of various neurotransmitters. A lack of SAMe can lead to depression, mood swings and various other psychological symptoms.

Due to its far-reaching effects on folic acid and SAMe, methylcobalamin plays an important role in the normal functioning of the nervous system and proper cell division.

This second natural bioactive form of B12 can also be directly utilized by the body. This form of vitamin B12 is the most abundant one in our nutritional intake, and it is also the one most present in all tissues and organs (especially in the liver).

Adenosylcobalamin acts directly in the mitochondria, where its effect in the citrate cycle is crucial, for the formation of cell energy.

It activates the enzyme methylmalonyl-CoA mutase, which is important for the production of fatty acids and the formation of the DNA building blocks. A lack of adenosylcobalamin can lead to neurological and cognitive disorders, underweight, chronic fatigue and muscle weakness.

This is the most common form of vitamin B12 in our diet and blood. Hydroxocobalamin is bound to the body's own transport molecules, having an excellent depot-storage function. This natural precursor is converted either into the bioactive methylcobalamin or adenosylcobalamin, as necessary, ensuring a consistent, long-lasting supply of vitamin B12.

Vitamin B12 Synergy does not contain cyanocobalamin. It is an inactive form of B12, which has to be converted in the body in several stages, into another form of vitamin B12. Since it has poorer bio-availability and cannot be activated in certain people with metabolic disorders, cyanocobalamin is not recommended by experts.

Vitality Nutritionals formulations are free from impurities, articial flavourings and artificial sweeteners. Vegan or vegetarian ingredients are used where possible, and every product is non-GMO.

• free from lactose, soy, gluten, yeast
• free from wheat and dairy products
• free from artificial colors and preservatives
• free from genetically modified substances
• free from animal products
• suitable for Vegetarians, Vegans and Diabetics